Surgical excision margins for primary cutaneous melanoma

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Surgical excision margins for primary cutaneous melanoma.

BACKGROUND Cutaneous melanoma accounts for 75% of skin cancer deaths. Standard treatment is surgical excision with a safety margin some distance from the borders of the primary tumour. The purpose of the safety margin is to remove both the complete primary tumour and any melanoma cells that might have spread into the surrounding skin.Excision margins are important because there could be trade-o...

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Primary excision of cutaneous melanoma.

It seemed almost inevitable that there would be a secondary care backlash towards GPs being 'let loose' with a scalpel ('Primary excision of cutaneous melanoma'). Any GP practising regular minor surgery sessions over many years will surely unwittingly excise the very occasional malignant skin lesion. I have no doubt that dermatologists occasionally mistakenly excise a benign one! Are we not in ...

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Primary excision of cutaneous melanoma.

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2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: a randomised, multicentre trial.

BACKGROUND Optimum surgical resection margins for patients with clinical stage IIA-C cutaneous melanoma thicker than 2 mm are controversial. The aim of the study was to test whether survival was different for a wide local excision margin of 2 cm compared with a 4-cm excision margin. METHODS We undertook a randomised controlled trial in nine European centres. Patients with cutaneous melanoma t...

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Excision margins for primary cutaneous melanoma: updated pooled analysis of randomized controlled trials.

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2009

ISSN: 1465-1858

DOI: 10.1002/14651858.cd004835.pub2